05/21/2025
🎉 We are excited to announce the integration of the MATISSE pocket binding similarity algorithm (by SoftMining) into Biovista Vizit! 🎉
MATISSE uses short (MD) simulations to uncover the flexible nature of active sites, enabling advanced structured-based analyses.
Biovista Vizit now offers integrative workflows that enable more sophisticated hashtag scenarios, e.g:
-Start from a target of interest
-Explore related PDB structures
-Expand across structurally similar binding pockets—even across unrelated proteins
-Discover and repurpose compounds linked to those structures
-Visualize them in 3D via integrated Mol Viewer links
This is Vizit’s fourth corpus integration, following , , and hashtag , and a significant step towards deeper, structure-based drug discovery and drug repurposing workflows.
This technology preview is the result of the ongoing collaboration between Biovista and SoftMining, and is co-funded by the EU Project NewRoad.
https://www.biovista.com/biovista-vizit-new-corpus-matisse-a-softmining-algorithm/
By Eftychia Lekka and Vassilis Virvilis The latest release of Biovista Vizit (May 2025) brings the integration of the MATISSE pocket binding similarity algorithm by SoftMining. MATISSE is a dynamic binding pocket analysis tool that uses short molecular dynamics (MD) simulations to capture the flexib...