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For over 100 years, scientists, patent professionals, and business leaders have relied on CAS to accelerate breakthroughs and improve lives. As a leader in scientific information solutions, we curate, connect, and analyze the world’s published science to accelerate breakthroughs. CAS Solutions: Connecting research, patent, regulatory, and business professionals to the data and insights they need,

our solutions speed progress through each phase of your pipeline. CAS Expertise: Our team of scientists and technologists embody a wealth of experience across disciplines and collectively speak more than 50 languages fueling our unique capabilities and insights. CAS Data: Our scientists curate, connect, and analyze the valuable data disclosed in scientific publications from around the world to build the CAS Content Collection™, covering over 150 years of discoveries. Our Team: Our team of over 1,000 scientists, technologists, and business professionals are passionate about advancing science and collectively speak more than 50 languages. We are proudly headquartered in Columbus, Ohio, with global offices in 45+ countries. Our History: Founded in 1907 as a volunteer effort to organize published chemistry research, CAS officially became a self-supporting division of the American Chemical Society in 1956.

There’s still time to register for this Thursday’s CAS and Eli Lilly and Company webinar, “Decoding Decades of   in Proc...
08/31/2026

There’s still time to register for this Thursday’s CAS and Eli Lilly and Company webinar, “Decoding Decades of in Process .” Reserve your spot now: https://bit.ly/4gBX9uD

Classical   evaluation assumes there is one correct answer. Language models and   systems break that assumption. 5 emerg...
08/31/2026

Classical evaluation assumes there is one correct answer. Language models and systems break that assumption. 5 emerging approaches are changing how we measure whether AI can actually be trusted. See how: https://bit.ly/3S4NzqO

Classical accuracy metrics assume one correct answer per question. Language models (LLMs) and agentic AI break that assumption. Learn about evaluation approaches emerging for scientific AI.

Stay up-to-date with the latest with   AI. Watch a recording of our recent   where we demonstrate ways to use   in synth...
08/28/2026

Stay up-to-date with the latest with AI. Watch a recording of our recent where we demonstrate ways to use in synthetic planning: https://bit.ly/4wOagO4

  data scattered across siloed systems and incompatible formats can't power your next breakthrough. CAS partners with R&...
08/27/2026

data scattered across siloed systems and incompatible formats can't power your next breakthrough. CAS partners with R&D teams to curate and structure that into an -ready foundation. See how: https://bit.ly/4vVfeZO

A joint report with   SAMRI pairs CAS-indexed chemical substance   with NLP to map emerging   topics. The result is a cl...
08/26/2026

A joint report with SAMRI pairs CAS-indexed chemical substance with NLP to map emerging topics. The result is a clearer view of where research momentum is actually building. Read more about the findings.

To better understand the state of global polymer innovation, CAS and PetroChina (Shanghai) Advanced Materials Research Institute Co. (SAMRI) developed Polymer Frontiers: A Comprehensive Data-Driven Analysis of Emerging Trends.

The   market generates nearly $50B annually, yet most patients with PD-L1 positive tumors still do not respond to first-...
08/25/2026

The market generates nearly $50B annually, yet most patients with PD-L1 positive tumors still do not respond to first-line checkpoint . The next wave of targets in Phase I through III trials will define where R&D investment flows next. See the full landscape: https://bit.ly/3SI7KLj

Natural   are fragile, expensive, and require cold storage.   mimic their catalytic activity using stable, tunable  . An...
08/25/2026

Natural are fragile, expensive, and require cold storage. mimic their catalytic activity using stable, tunable . An analysis of 14,500+ publications maps where this emerging field is headed: https://bit.ly/4zsqbUY

Our upcoming   shows how a CAS and Eli Lilly and Company analysis of more than 34,000 published reactions maps process  ...
08/24/2026

Our upcoming shows how a CAS and Eli Lilly and Company analysis of more than 34,000 published reactions maps process changes between 2000 and 2025. Learn about findings related to , , and reaction conditions. https://bit.ly/4gBX9uD

An analysis of 40K+ composting publications and   shows that   and machine learning are shifting industrial   from react...
08/24/2026

An analysis of 40K+ composting publications and shows that and machine learning are shifting industrial from reactive management to predictive control. Maturity forecasting, anomaly detection, and are already in use. See how far it's come: https://bit.ly/4uWbcz9

Composting has evolved into a precision-engineered bioprocess. See how aeration, microbial control, materials science, and AI are reshaping the field.

Meet us in the American Chemical Society booth this week at   to demo our latest AI-enhanced capabilities in  . Then, st...
08/23/2026

Meet us in the American Chemical Society booth this week at to demo our latest AI-enhanced capabilities in . Then, stay for our presentation, where you’ll learn how our science-smart technology can transform the way you . https://bit.ly/4glrDzD

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